1. Introduction Chronic idiopathic constipation (CIC) is a common gastrointestinal disorder characterized by infrequent bowel movements, difficult stool passage, and incomplete evacuation. It significantly impacts patients' quality of life and is more prevalent among women. Despite various treatments, some patients fail to respond to conventional therapies, prompting interest in...

Clinical summary [1] To date, there is no effective treatment for irritable bowel syndrome (IBS-C), which is characterized by significant constipation symptoms. Probiotics have been recognized as having the potential to relieve symptoms associated with IBS-C. [2] The purpose of this clinical efficacy study, conducted by the MicroCare Probiotics Institute in conjunction with relevant...

Abstract:This article presents a comprehensive safety evaluation of Bifidobacterium animalis subsp. lactis BLa80, a new probiotic strain with potential applications in the food industry. The safety assessment was conducted through in vitro assays simulating gastrointestinal conditions, genomic analysis, and a 90-day oral toxicity test in rats. The strain demonstrated high survival...